Major projects in the Bowdish lab:

  1. Understanding the origins of healthy/unhealthy aging.
  2. Elucidating how the aging gut microbiome contributes to age-associated inflammation
  3. Uncovering how age-associated inflammation alters the maturation and function of monocytes and macrophages and how these changes increase susceptibility to pneumonia.
  4. Discovering how age-related changes in the upper respiratory microbiota contribute to susceptibility to pneumonia
  5. Developing novel strategies to prevent pneumonia in vulnerable populations
  6. Characterizing the role of the macrophage scavenger receptors in host defence