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Bowdish Lab

Macrophage Biology at McMaster University

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    • Vaccination and infection in older adults
    • Age, pneumonia, and post-pneumonia health issues
    • The role of the microbiota in healthy/unhealthy aging
    • Uncovering how age-associated inflammation alters the maturation and function of monocytes and macrophages.
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Antibody Production & Purification

Protein A Sepharose purification of Antibodies

  • This protocol is useful for purifying antibodies from hybridoma cultures and serum.

Immunization protocol for rabbits

  • This protocol is used for generating polyclonal antibodies to peptide ligands in rabbits.
  • Citation: Novakowski KE, et al.A naturally occurring transcript variant of MARCO reveals the SRCR domain is critical for function. Immunol Cell Biol. 2016 Aug;94(7):646-55.

Dawn Bowdish

Recent Lab News

  • CBC’s Quirks and Quarks ‘Scientific Sovereignty — How Canadian scientists are coping with U.S. cuts and chaos’ featuring Dr. Bowdish and MD/PhD candidate Kevin Zhao
  • The Agenda: Why aren’t more kids vaccinated against measles? With Dr. Bowdish and other experts.
  • Publication: Minimal Impact of Prior Common Cold Coronavirus Exposure on Immune Responses to Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination or Infection Risk in Older Adults in Congregate Care
  • Post-doctoral position in Human Immunology Available
  • The Bowdish lab is no longer accepting thesis student applications for the 2025/26 academic year.
  • Publication: Canadian Immunity Task Force (CITF) Hema-Net Serosurveillance Meeting
  • “The Perils of Being Born in the Fall” will be at the Zoetic Theatre November, 12, 2024
  • Dr. Bowdish speaks at the 2024 Innovation Nation Conference & Student Innovation Showcase
  • Dr. Bowdish discusses COVID-19 on The Agenda with Steve Paikin
  • Publication: Reassuring humoral and cellular immune responses to SARS-CoV-2 vaccination in participants with systemic sclerosis

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