{"id":3356,"date":"2023-12-20T16:54:06","date_gmt":"2023-12-20T21:54:06","guid":{"rendered":"https:\/\/www.bowdish.ca\/lab\/?p=3356"},"modified":"2023-12-30T22:59:05","modified_gmt":"2023-12-31T03:59:05","slug":"dr-jessica-breznik-talks-about-her-research-in-the-american-journal-of-physiology-gastrointestinal-and-liver-physiology-podcast","status":"publish","type":"post","link":"https:\/\/www.bowdish.ca\/lab\/2023\/12\/20\/dr-jessica-breznik-talks-about-her-research-in-the-american-journal-of-physiology-gastrointestinal-and-liver-physiology-podcast\/","title":{"rendered":"Dr. Jessica Breznik talks about her research  in the American Journal of Physiology-Gastrointestinal and Liver Physiology Podcast"},"content":{"rendered":"\n<p>In this <a href=\"https:\/\/ajpgi.podbean.com\/e\/got-guts-the-micro-version-with-jessica-a-breznik\/\">podcast<\/a> first author Dr. Jessica A. Breznik of McMaster University, discusses the recently published manuscript titled &#8220;Diet-induced obesity alters intestinal monocyte-derived and tissue-resident macrophages and increases intestinal permeability in female mice independent of tumor necrosis factor.&#8221;\u00a0<\/p>\n\n\n\n<p><strong>NEW &amp; NOTEWORTHY<\/strong>&nbsp;We found that diet-induced obesity in female mice has tissue- and time-dependent effects on intestinal paracellular permeability as well as monocyte-derived and tissue-resident macrophage numbers, surface marker phenotype, and intracellular production of the cytokines IL-10 and TNF. These changes were not mediated by TNF.<\/p>\n\n\n\n<p><strong>Article Citation:&nbsp;<\/strong><a href=\"https:\/\/journals.physiology.org\/doi\/abs\/10.1152\/ajpgi.00231.2022\">Diet-induced obesity alters intestinal monocyte-derived and tissue-resident macrophages and increases intestinal permeability in female mice independent of tumor necrosis factor<\/a>Jessica A. Breznik,&nbsp;Jennifer Jury,&nbsp;Elena F. Verd\u00fa,&nbsp;Deborah M. Sloboda, and&nbsp;Dawn M. E. Bowdish<\/p>\n\n\n\n<p>American Journal of Physiology-Gastrointestinal and Liver Physiology&nbsp;2023&nbsp;324:4,&nbsp;G305-G321<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In this podcast first author Dr. Jessica A. Breznik of McMaster University, discusses the recently published manuscript titled &#8220;Diet-induced obesity alters intestinal monocyte-derived and tissue-resident macrophages and increases intestinal permeability in female mice independent of tumor necrosis factor.&#8221;\u00a0 NEW &amp; &hellip; <a href=\"https:\/\/www.bowdish.ca\/lab\/2023\/12\/20\/dr-jessica-breznik-talks-about-her-research-in-the-american-journal-of-physiology-gastrointestinal-and-liver-physiology-podcast\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,85],"tags":[87,12,48],"class_list":["post-3356","post","type-post","status-publish","format-standard","hentry","category-news","category-publications","tag-inflammation","tag-macrophage","tag-post-doc"],"_links":{"self":[{"href":"https:\/\/www.bowdish.ca\/lab\/wp-json\/wp\/v2\/posts\/3356","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bowdish.ca\/lab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bowdish.ca\/lab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bowdish.ca\/lab\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bowdish.ca\/lab\/wp-json\/wp\/v2\/comments?post=3356"}],"version-history":[{"count":1,"href":"https:\/\/www.bowdish.ca\/lab\/wp-json\/wp\/v2\/posts\/3356\/revisions"}],"predecessor-version":[{"id":3357,"href":"https:\/\/www.bowdish.ca\/lab\/wp-json\/wp\/v2\/posts\/3356\/revisions\/3357"}],"wp:attachment":[{"href":"https:\/\/www.bowdish.ca\/lab\/wp-json\/wp\/v2\/media?parent=3356"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bowdish.ca\/lab\/wp-json\/wp\/v2\/categories?post=3356"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bowdish.ca\/lab\/wp-json\/wp\/v2\/tags?post=3356"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}